RAP1GAP anticorps (AA 460-540)

N° du produit ABIN7216788

Cet anticorps Lapin Polyclonal détecte spécifiquement RAP1GAP dans WB, ELISA et IHC (p). Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour RAP1GAP anticorps (AA 460-540) (ABIN7216788)

Antigène: RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAP1GAP est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-RAP1GAP anticorps

Épitope: AA 460-540

Fonction: Rap1GAP Polyclonal Antibody

Specificité: Rap1GAP Polyclonal Antibody detects endogenous levels of Rap1GAP protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the C-terminal region of human Rap1GAP at AA range: 460-540

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur RAP1GAP

Antigène: RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))

Autre désignation: Rap1GAP

Sujet: Rabbit Anti-Rap1GAP Polyclonal Antibody,RAP1GAP, KIAA0474, RAP1GA1, Rap1 GTPase-activating protein 1, Rap1GAP, Rap1GAP1,RAP1GAP encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form. The product of this gene, RAP1GAP, promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins, guanine nucleotide exchange factors (GEFs), act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form. In general, ras subfamily proteins, such as RAP1, play key roles in receptor-linked signaling pathways that control cell growth and differentiation. RAP1 plays a role in diverse processes such as cell proliferation, adhesion, differentiation, and embryogenesis. Alternative splicing results in multiple transcript variants encoding distinct proteins.,Rap1 GTPase-activating protein 1

Poids moléculaire: observerd band 73kDa

ID gène: 5909

UniProt: P47736