RIN1 anticorps (AA 630-710)

N° du produit ABIN7226044

Cet anticorps anti-RIN1 est un anticorps Lapin Polyclonal détectant RIN1 dans ELISA et WB. Adapté pour Humain, Rat et Souris.

Aperçu rapide pour RIN1 anticorps (AA 630-710) (ABIN7226044)

Antigène: RIN1 (Ras and Rab Interactor 1 (RIN1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RIN1 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-RIN1 anticorps

Épitope: AA 630-710

Fonction: RIN1 Polyclonal Antibody

Specificité: RIN1 Polyclonal Antibody detects endogenous levels of RIN1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the C-terminal region of human RIN1 at AA range: 630-710

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur RIN1

Antigène: RIN1 (Ras and Rab Interactor 1 (RIN1))

Autre désignation: RIN1

Sujet: Rabbit Anti-RIN1 Polyclonal Antibody,RIN1, Ras and Rab interactor 1, Ras inhibitor JC99, Ras interaction/interference protein 1,Ras is a membrane-associated small G protein that is indirectly coupled to receptor and nonreceptor tyrosine kinases. Ras activation is regulated by the levels of bound GTP and GDP. Several effectors of Ras have been identified, including Raf1, PI 3-kinase and RIN1. RIN1 (Ras interaction/interference) was identified as a Ras-interacting protein in yeast, and it has been shown to bind to the human H-Ras. This RIN1-Ras interaction is enhanced when Ras is bound to GTP. Unlike Raf1, RIN1 is localized primarily to the plasma membrane. RIN1 contains an SH2 domain and an amino-terminal region similar to consensus SH3 domains. RIN1 binds c-Abl and, like Raf1, interacts with 14-3-3 proteins.,Ras and Rab interactor 1

Poids moléculaire: observerd band 84kDa

ID gène: 9610

UniProt: Q13671