RIN2 anticorps (AA 70-150)

N° du produit ABIN7231058

Cet anticorps Lapin Polyclonal détecte spécifiquement RIN2 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour RIN2 anticorps (AA 70-150) (ABIN7231058)

Antigène: RIN2 (Ras and Rab Interactor 2 (RIN2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RIN2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-RIN2 anticorps

Épitope: AA 70-150

Fonction: Rabbit Anti-RIN2 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of RIN2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human RIN2 protein at AA range: 70-150

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur RIN2

Antigène: RIN2 (Ras and Rab Interactor 2 (RIN2))

Autre désignation: RIN2

Sujet: Ras and Rab interactor 2, Ras association domain family 4, Ras inhibitor JC265, Ras interaction/interference protein 2The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by RIN2 (Ras And Rab Interactor 2) binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in RIN2 cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 98kD

ID gène: 54453

UniProt: Q8WYP3