RASA4 anticorps (AA 100-180)
Aperçu rapide pour RASA4 anticorps (AA 100-180) (ABIN7230954)
Antigène
Voir toutes RASA4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 100-180
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Fonction
- RASL2 Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of RASL2 protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogène
- Synthesized peptide derived from part region of human RASL2 protein at AA range: 100-180
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- RASA4 (RAS P21 Protein Activator 4 (RASA4))
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Autre désignation
- RASL2
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Sujet
- Rabbit Anti-RASL2 Polyclonal Antibody,Ras GTPase-activating protein 4, Calcium-promoted Ras inactivator, Ras p21 protein activator 4, RasGAP-activating-like protein 2,RASA4 (RAS P21 Protein Activator 4) encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for RASA4.,RASL2
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Poids moléculaire
- observerd band 88kDa
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ID gène
- 10156
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UniProt
- O43374
Antigène
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