RASA4 anticorps (AA 100-180)

N° du produit ABIN7230954

Cet anticorps Lapin Polyclonal détecte spécifiquement RASA4 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour RASA4 anticorps (AA 100-180) (ABIN7230954)

Antigène: RASA4 (RAS P21 Protein Activator 4 (RASA4))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RASA4 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-RASA4 anticorps

Épitope: AA 100-180

Fonction: Rabbit Anti-RASL2 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of RASL2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human RASL2 protein at AA range: 100-180

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur RASA4

Antigène: RASA4 (RAS P21 Protein Activator 4 (RASA4))

Autre désignation: RASL2

Sujet: Ras GTPase-activating protein 4, Calcium-promoted Ras inactivator, Ras p21 protein activator 4, RasGAP-activating-like protein 2RASA4 (RAS P21 Protein Activator 4) encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for RASA4.

Poids moléculaire: 88kD

ID gène: 10156

UniProt: O43374