RERG anticorps (AA 70-150)

N° du produit ABIN7225492

Cet anticorps anti-RERG Polyclonal Lapin (ABIN7225492) détecte spécifiquement RERG dans ELISA, IHC et IF. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour RERG anticorps (AA 70-150) (ABIN7225492)

Antigène: RERG (RAS-Like, Estrogen-Regulated, Growth Inhibitor (RERG))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RERG est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-RERG anticorps

Épitope: AA 70-150

Fonction: Rabbit Anti-RERG Polyclonal Antibody

Specificité: RERG Polyclonal Antibody detects endogenous levels of RERG protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human RERG at AA range: 70-150

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur RERG

Antigène: RERG (RAS-Like, Estrogen-Regulated, Growth Inhibitor (RERG))

Autre désignation: RERG

Sujet: RERG, Ras-related and estrogen-regulated growth inhibitorMembers of the Ras superfamily of small GTP-binding proteins are critical mediators of diverse cell signaling pathways, including those leading to cell proliferation, cytoskeletal organization and secretion. RERG (RAS-like, estrogen-regulated, growth inhibitor) is a 199 amino acid protein that localizes to the cytoplasm and belongs to the Ras subfamily of small GTPases. Expressed in pancreas, liver, skin, lung, brain, kidney and heart tissue, RERG possesses intrinsic GTPase activity and is able to bind both GDP and GTP and, when overexpressed, may reduce overall tumorigenic potential. RERGL, also known as ras-related and estrogen-regulated growth inhibitor-like protein, is a 205 amino acid protein that belongs to the small GTPase superfamily as well as the Ras family. RERGL binds GDP/GTP and may possess intrinsic GTPase activity. The RERGL gene is conserved in chimpanzee, dog, mouse, rat, chicken, zebrafish and mosquito, and maps to human chromosome 12p12.3.

ID gène: 85004

UniProt: Q96A58