RCAN1 anticorps (AA 180-260)
Aperçu rapide pour RCAN1 anticorps (AA 180-260) (ABIN7214630)
Antigène
Voir toutes RCAN1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 180-260
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Fonction
- DSCR 1 Polyclonal Antibody
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Specificité
- DSCR 1 Polyclonal Antibody detects endogenous levels of DSCR 1 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from the C-terminal region of human DSCR 1 at AA range: 180-260
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- RCAN1 (Regulator of Calcineurin 1 (RCAN1))
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Autre désignation
- DSCR 1
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Sujet
- Rabbit Anti-DSCR 1 Polyclonal Antibody,RCAN1, ADAPT78, CSP1, DSC1, DSCR1, Calcipressin-1, Adapt78, Down syndrome critical region protein 1, Myocyte-enriched calcineurin-interacting protein 1, MCIP1, Regulator of calcineurin 1,Regulator of calcineurin 1 encoded by RCAN1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of RCAN1 may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants.,Calcipressin-1
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Poids moléculaire
- observerd band 22kDa
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ID gène
- 1827
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UniProt
- P53805
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Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Antigène
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