RTN4RL2 anticorps (AA 290-370)

N° du produit ABIN7230866

Cet anticorps anti-RTN4RL2 est un anticorps Lapin Polyclonal détectant RTN4RL2 dans WB et ELISA. Adapté pour Humain, Rat et Souris.

Aperçu rapide pour RTN4RL2 anticorps (AA 290-370) (ABIN7230866)

Antigène: RTN4RL2 (Reticulon 4 Receptor-Like 2 (RTN4RL2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RTN4RL2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-RTN4RL2 anticorps

Épitope: AA 290-370

Fonction: R4RL2 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of R4RL2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human R4RL2 protein at AA range: 290-370

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur RTN4RL2

Antigène: RTN4RL2 (Reticulon 4 Receptor-Like 2 (RTN4RL2))

Autre désignation: R4RL2

Sujet: Rabbit Anti-R4RL2 Polyclonal Antibody,Nogo receptor-like 3, Nogo-66 receptor homolog 1, Nogo-66 receptor-related protein 2, NgR2,RTN4RL2 (Reticulon 4 Receptor Like 2) is a Protein Coding gene. Among its related pathways are Metabolism of proteins and Post-translational modification- synthesis of GPI-anchored proteins. GO annotations related to this gene include receptor activity. An important paralog of this gene is RTN4RL1. Cell surface receptor that plays a functionally redundant role in the inhibition of neurite outgrowth mediated by MAG (By similarity). Plays a functionally redundant role in postnatal brain development. Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum. Does not seem to play a significant role in regulating axon regeneration in the adult central nervous system. Protects motoneurons against apoptosis, protection against apoptosis is probably mediated by MAG (By similarity). Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development (PubMed: 22325200). Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton (PubMed: 22325200).,R4RL2

Poids moléculaire: observerd band 46kDa

ID gène: 349667

UniProt: Q86UN3