ARHGAP24 anticorps (AA 550-630)

N° du produit ABIN7231038

Cet anticorps anti-ARHGAP24 Polyclonal Lapin (ABIN7231038) détecte spécifiquement ARHGAP24 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ARHGAP24 anticorps (AA 550-630) (ABIN7231038)

Antigène: ARHGAP24 (rho GTPase Activating Protein 24 (ARHGAP24))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGAP24 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ARHGAP24 anticorps

Épitope: AA 550-630

Fonction: Rabbit Anti-RHG24 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of RHG24 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human RHG24 protein at AA range: 550-630

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur ARHGAP24

Antigène: ARHGAP24 (rho GTPase Activating Protein 24 (ARHGAP24))

Autre désignation: RHG24

Sujet: Rho GTPase-activating protein 24, Filamin-A-associated RhoGAP, FilGAP, RAC1- and CDC42-specific GTPase-activating protein of 72 kDa, RC-GAP72, Rho-type GTPase-activating protein 24, RhoGAP of 73 kDa, Sarcoma antigen NY-SAR-88, p73RhoGAPARHGAP24 (Rho GTPase Activating Protein 24) is a Protein Coding gene. Diseases associated with ARHGAP24 include Glomerulosclerosis, Focal Segmental, 1 and Atypical Autism. Among its related pathways are G-protein signaling_Regulation of RAC1 activity and p75 NTR receptor-mediated signalling. ARHGAP24 encodes a Rho-GTPase activating protein, which is specific for the small GTPase family member Rac. Binding of the encoded protein by filamin A targets it to sites of membrane protrusion, where it antognizes Rac. This results in suppression of lamellae formation and promotion of retraction to regulate cell polarity. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 82kD

ID gène: 83478

UniProt: Q8N264

Pathways: Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus