ARHGEF2 anticorps (pSer885)

N° du produit ABIN7225862

L’anticorps anti-ARHGEF2 Polyclonal Lapin est utilisé pour la détection de ARHGEF2 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IHC et IF.

Aperçu rapide pour ARHGEF2 anticorps (pSer885) (ABIN7225862)

Antigène: ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGEF2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-ARHGEF2 anticorps

Épitope: pSer885

Fonction: Rabbit Anti-Lfc (phospho Ser885) Polyclonal Antibody

Specificité: Phospho-Lfc (S885) Polyclonal Antibody detects endogenous levels of Lfc protein only when phosphorylated at S885.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human Lfc Phospho-Ser885

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur ARHGEF2

Antigène: ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))

Autre désignation: Lfc

Sujet: ARHGEF2, KIAA0651, LFP40, Rho guanine nucleotide exchange factor 2, Guanine nucleotide exchange factor H1, GEF-H1, Microtubule-regulated Rho-GEF, Proliferating cell nucleolar antigen p40Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The protein encoded by ARHGEF2 (Rho/Rac guanine nucleotide exchange factor 2)may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified.

Poids moléculaire: 111kD

ID gène: 9181

UniProt: Q92974

Pathways: Negative Regulation of intrinsic apoptotic Signaling