RNF14 anticorps (AA 330-410)

N° du produit ABIN7226042

L’anticorps anti-RNF14 Polyclonal Lapin est utilisé pour la détection de RNF14 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour RNF14 anticorps (AA 330-410) (ABIN7226042)

Antigène: RNF14 (Ring Finger Protein 14 (RNF14))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF14 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-RNF14 anticorps

Épitope: AA 330-410

Fonction: Rabbit Anti-ARA54 Polyclonal Antibody

Specificité: ARA54 Polyclonal Antibody detects endogenous levels of ARA54 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the C-terminal region of human ARA54 at AA range: 330-410

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur RNF14

Antigène: RNF14 (Ring Finger Protein 14 (RNF14))

Autre désignation: ARA54

Sujet: RNF14, ARA54, HRIHFB2038, E3 ubiquitin-protein ligase RNF14, Androgen receptor-associated protein 54, HFB30, RING finger protein 14, Triad2 proteinThe protein encoded by RNF14 (ring finger protein 14) contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of RNF14 has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Six alternatively spliced transcript variants encoding two distinct isoforms have been reported.

Poids moléculaire: 50kD

ID gène: 9604

UniProt: Q9UBS8

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling