SIAH1/2 anticorps (AA 160-240)
Aperçu rapide pour SIAH1/2 anticorps (AA 160-240) (ABIN7217010)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 160-240
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Fonction
- Siah-1/2 Polyclonal Antibody
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Specificité
- Siah-1/2 Polyclonal Antibody detects endogenous levels of Siah-1/2 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from the Internal region of human Siah-1/2 at AA range: 160-240
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- SIAH1/2 (Seven in Absentia Homolog 1/2 (SIAH1/2))
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Autre désignation
- Siah-1/2
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Sujet
- Rabbit Anti-Siah-1/2 Polyclonal Antibody,SIAH1, HUMSIAH, E3 ubiquitin-protein ligase SIAH1, Seven in absentia homolog 1, Siah-1, Siah-1a, SIAH2, E3 ubiquitin-protein ligase SIAH2, Seven in absentia homolog 2, Siah-2, hSiah2,SIAH1 encodes E3 ubiquitin-protein ligase SIAH1 that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.,E3 ubiquitin-protein ligase SIAH1
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Poids moléculaire
- observerd band 34kDa
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ID gène
- 6477, 6478
Antigène
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