SH3BP1 anticorps (AA 170-250)

N° du produit ABIN7227092

Cet anticorps anti-SH3BP1 Polyclonal Lapin (ABIN7227092) détecte spécifiquement SH3BP1 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour SH3BP1 anticorps (AA 170-250) (ABIN7227092)

Antigène: SH3BP1 (SH3-Domain Binding Protein 1 (SH3BP1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SH3BP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-SH3BP1 anticorps

Épitope: AA 170-250

Fonction: Rabbit Anti-3BP1 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of 3BP1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human 3BP1 protein at AA range: 170-250

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur SH3BP1

Antigène: SH3BP1 (SH3-Domain Binding Protein 1 (SH3BP1))

Autre désignation: 3BP1

Sujet: SH3 domain-binding protein 1SH3BP1 encodes a member of the Rho GTPase activating protein (RhoGAP) family. The encoded protein regulates Rac signaling and plays a role in cytoskeletal dynamics, cell motility and epithelial junction formation. This protein's association with the exocyst complex, which tethers secretory vesicles to the plasma membrane, has been demonstrated to be important in cell motility. In a distinct complex, this protein has been shown to regulate epithelial junction formation and morphogenesis. By interacting with the Plexin-D1 cell surface receptor, this protein mediates changes in the cytoskeleton in response to semaphorin binding. This protein may promote metastasis in human liver cancer cells and tissues.

Poids moléculaire: 77kD

ID gène: 23616

UniProt: Q9Y3L3