SIGLEC-5,SIGLEC-14 (Internal Region) anticorps
Aperçu rapide pour SIGLEC-5,SIGLEC-14 (Internal Region) anticorps (ABIN7218076)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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Fonction
- Siglec-5/14 Polyclonal Antibody
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Specificité
- Siglec-5/14 Polyclonal Antibody detects endogenous levels of Siglec-5/14 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from the Internal region of human Siglec-5/14
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- SIGLEC-5,SIGLEC-14
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Autre désignation
- Siglec-5/14
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Sujet
- Rabbit Anti-Siglec-5/14 Polyclonal Antibody,SIGLEC5, CD33L2, OBBP2, Sialic acid-binding Ig-like lectin 5, Siglec-5, CD33 antigen-like 2, Obesity-binding protein 2, OB-BP2, OB-binding protein 2, CD170, SIGLEC14, Sialic acid-binding Ig-like lectin 14, Siglec-14,SIGLEC5 encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The sialic acid binding Ig like lectin 5 is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.,Sialic acid-binding Ig-like lectin 5
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Poids moléculaire
- observerd band 60kDa
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ID gène
- 8778
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UniProt
- O15389
Antigène
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