SIGLEC-5,SIGLEC-14 (Internal Region) anticorps

N° du produit ABIN7218076

Cet anticorps Lapin Polyclonal détecte spécifiquement SIGLEC-5,SIGLEC-14 dans ELISA, IF, WB et IHC. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour SIGLEC-5,SIGLEC-14 (Internal Region) anticorps (ABIN7218076)

Antigène: SIGLEC-5,SIGLEC-14

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: ELISA, Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit

Épitope: Internal Region

Fonction: Rabbit Anti-Siglec-5/14 Polyclonal Antibody

Specificité: Siglec-5/14 Polyclonal Antibody detects endogenous levels of Siglec-5/14 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human Siglec-5/14

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détail du antigène

Antigène: SIGLEC-5,SIGLEC-14

Autre désignation: Siglec-5/14

Sujet: SIGLEC5, CD33L2, OBBP2, Sialic acid-binding Ig-like lectin 5, Siglec-5, CD33 antigen-like 2, Obesity-binding protein 2, OB-BP2, OB-binding protein 2, CD170, SIGLEC14, Sialic acid-binding Ig-like lectin 14, Siglec-14SIGLEC5 encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The sialic acid binding Ig like lectin 5 is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.

ID gène: 8778

UniProt: O15389