ORCTL-2/SLC22A18 anticorps (AA 330-410)

N° du produit ABIN7216332

Cet anticorps anti-ORCTL-2/SLC22A18 Polyclonal Lapin (ABIN7216332) détecte spécifiquement ORCTL-2/SLC22A18 dans WB, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ORCTL-2/SLC22A18 anticorps (AA 330-410) (ABIN7216332)

Antigène: ORCTL-2/SLC22A18 (SLC22A18) (Solute Carrier Family 22 Member 18 (SLC22A18))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ORCTL-2/SLC22A18 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-ORCTL-2/SLC22A18 anticorps

Épitope: AA 330-410

Fonction: Rabbit Anti-ORCTL2 Polyclonal Antibody

Specificité: ORCTL2 Polyclonal Antibody detects endogenous levels of ORCTL2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the C-terminal region of human ORCTL2 at AA range: 330-410

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur ORCTL-2/SLC22A18

Antigène: ORCTL-2/SLC22A18 (SLC22A18) (Solute Carrier Family 22 Member 18 (SLC22A18))

Autre désignation: ORCTL2

Sujet: SLC22A18, BWR1A, BWSCR1A, HET, IMPT1, ITM, ORCTL2, SLC22A1L, TSSC5, Solute carrier family 22 member 18, Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene A protein, Efflux transporter-like protein, Imprinted multi-membrane-spaSLC22A18 is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15. , an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. SLC22A18 is imprinted, with preferential expression from the maternal allele. Mutations in SLC22A18 have been found in Wilms' tumor and lung cancer. Solute carrier family 22 member 18 may act as a transporter of organic cations, and have a role in the transport of chloroquine and quinidine-related compounds in kidney. Several alternatively spliced transcript variants encoding different isoforms have been described.

Poids moléculaire: 43kD

ID gène: 5002

UniProt: Q96BI1