SYNE2 anticorps (AA 360-440)
Aperçu rapide pour SYNE2 anticorps (AA 360-440) (ABIN7231618)
Antigène
Voir toutes SYNE2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 360-440
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Fonction
- Rabbit Anti-SYNE2 Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of SYNE2 protein
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from part region of human SYNE2 protein at AA range: 360-440
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300,IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- SYNE2 (Spectrin Repeat Containing, Nuclear Envelope 2 (SYNE2))
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Autre désignation
- SYNE2
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Sujet
- Nesprin-2, KASH domain-containing protein 2, KASH2, Nuclear envelope spectrin repeat protein 2, Nucleus and actin connecting element protein, Protein NUANCE, Synaptic nuclear envelope protein 2, Syne-2SYNE2 (Spectrin Repeat Containing Nuclear Envelope Protein 2) is a Protein Coding gene. Diseases associated with SYNE2 include Emery-Dreifuss Muscular Dystrophy 5, Autosomal Dominant and Emery-Dreifuss Muscular Dystrophy 2, Ad. Among its related pathways are Meiosis and Ovarian Infertility Genes. The protein encoded by SYNE2 is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus.
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Poids moléculaire
- 757kD
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ID gène
- 23224
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UniProt
- Q8WXH0
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Pathways
- Maintenance of Protein Location
Antigène
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