S1PR1 anticorps (pThr236)

N° du produit ABIN7220118

Cet anticorps Lapin Polyclonal détecte spécifiquement S1PR1 dans WB, ELISA et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour S1PR1 anticorps (pThr236) (ABIN7220118)

Antigène: S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp S1PR1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-S1PR1 anticorps

Épitope: pThr236

Fonction: Rabbit Anti-EDG-1 (phospho Thr236) Polyclonal Antibody

Specificité: Phospho-EDG-1 (T236) Polyclonal Antibody detects endogenous levels of EDG-1 protein only when phosphorylated at T236.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human EDG-1 Phospho-Thr236

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur S1PR1

Antigène: S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

Autre désignation: EDG-1

Sujet: S1PR1, CHEDG1, EDG1, Sphingosine 1-phosphate receptor 1, S1P receptor 1, S1P1, Endothelial differentiation G-protein coupled receptor 1, Sphingosine 1-phosphate receptor Edg-1, S1P receptor Edg-1, CD antigen CD363The sphingosine-1-phosphate receptor 1 encoded by S1PR1 is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 42kD

ID gène: 1901

UniProt: P21453

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2