STMN4 anticorps (AA 110-190)
Aperçu rapide pour STMN4 anticorps (AA 110-190) (ABIN7225198)
Antigène
Voir toutes STMN4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 110-190
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Fonction
- RB3 Polyclonal Antibody
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Specificité
- RB3 Polyclonal Antibody detects endogenous levels of RB3 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from the C-terminal region of human RB3 at AA range: 110-190
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- STMN4 (Stathmin-Like 4 (STMN4))
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Autre désignation
- RB3
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Sujet
- Rabbit Anti-RB3 Polyclonal Antibody,STMN4, Stathmin-4, Stathmin-like protein B3, RB3,RB3 (Stathmin-4), encoded by STMN4 gene, is a neuron-specific homologue of the SCG10/stathmin family proteins, possessing a unique N-terminal membrane-associated domain and the stathmin-like domain at the C terminus, which promotes microtubule (MT) catastrophe and/or tubulin sequestering. Stathmin is a ubiquitous cytosolic phosphoprotein, preferentially expressed in the nervous system, and described as a relay integrating diverse intracellular signaling pathways. RB3 is consistently up-regulated in differentiated neuroblastoma cells, and stable expression of transfected RB3 could induce differentiation, suggesting a role of RB3 during neuroblastoma differentiation. Moreover, increased RB3 is a unique response protein in the stathmin-related proteins following optical nerve axotomy and RB3 may be a critical target for neurodegenerative diseases.,Stathmin-4
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Poids moléculaire
- observerd band 22kDa
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ID gène
- 81551
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UniProt
- Q9H169
Antigène
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