SMC1B anticorps (AA 110-190)
Aperçu rapide pour SMC1B anticorps (AA 110-190) (ABIN7231408)
Antigène
Voir toutes SMC1B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 110-190
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Fonction
- SMC1B Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of SMC1B protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogène
- Synthesized peptide derived from part region of human SMC1B protein at AA range: 110-190
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- SMC1B (Structural Maintenance of Chromosomes 1B (SMC1B))
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Autre désignation
- SMC1B
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Sujet
- Rabbit Anti-SMC1B Polyclonal Antibody,Structural maintenance of chromosomes protein 1B, SMC protein 1B, SMC-1-beta, SMC-1B,SMC1B (Structural Maintenance Of Chromosomes 1B) is a Protein Coding gene. Among its related pathways are Meiosis and Oocyte meiosis. An important paralog of this gene is SMC1A. Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment. Contributes to axial element (AE) formation and the organization of chromatin loops along the AE. Plays a key role in synapsis, recombination and chromosome movements. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I (By similarity).,SMC1B
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Poids moléculaire
- observerd band 135kDa
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ID gène
- 27127
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UniProt
- Q8NDV3
Antigène
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