SMC1B anticorps (AA 110-190)

N° du produit ABIN7231408

Cet anticorps anti-SMC1B Polyclonal Lapin (ABIN7231408) détecte spécifiquement SMC1B dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour SMC1B anticorps (AA 110-190) (ABIN7231408)

Antigène: SMC1B (Structural Maintenance of Chromosomes 1B (SMC1B))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMC1B est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-SMC1B anticorps

Épitope: AA 110-190

Fonction: Rabbit Anti-SMC1B Polyclonal Antibody

Specificité: The antibody detects endogenous levels of SMC1B protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human SMC1B protein at AA range: 110-190

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur SMC1B

Antigène: SMC1B (Structural Maintenance of Chromosomes 1B (SMC1B))

Autre désignation: SMC1B

Sujet: Structural maintenance of chromosomes protein 1B, SMC protein 1B, SMC-1-beta, SMC-1BSMC1B (Structural Maintenance Of Chromosomes 1B) is a Protein Coding gene. Among its related pathways are Meiosis and Oocyte meiosis. An important paralog of this gene is SMC1A. Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment. Contributes to axial element (AE) formation and the organization of chromatin loops along the AE. Plays a key role in synapsis, recombination and chromosome movements. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I (By similarity).

Poids moléculaire: 135kD

ID gène: 27127

UniProt: Q8NDV3