ST5 anticorps (AA 380-460)

N° du produit ABIN7217128

Cet anticorps anti-ST5 Polyclonal Lapin (ABIN7217128) détecte spécifiquement ST5 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour ST5 anticorps (AA 380-460) (ABIN7217128)

Antigène: ST5 (Suppression of Tumorigenicity 5 (ST5))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ST5 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ST5 anticorps

Épitope: AA 380-460

Fonction: Rabbit Anti-ST5 Polyclonal Antibody

Specificité: ST5 Polyclonal Antibody detects endogenous levels of ST5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human ST5 at AA range: 380-460

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur ST5

Antigène: ST5 (Suppression of Tumorigenicity 5 (ST5))

Autre désignation: ST5

Sujet: ST5, DENND2B, HTS1, Suppression of tumorigenicity 5 protein, DENN domain-containing protein 2B, HeLa tumor suppression 1ST5 was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. Suppression of tumorigenicity 5 protein encoded by ST5 contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified.

Poids moléculaire: 126kD

ID gène: 6764

UniProt: P78524