Synapsin III anticorps
Aperçu rapide pour Synapsin III anticorps (ABIN7231616)
Antigène
Voir toutes Synapsin III (SYN3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- SYN3 Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of SYN3 protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogène
- Synthesized peptide derived from part region of human SYN3 protein
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Synapsin III (SYN3)
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Autre désignation
- SYN3
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Sujet
- Rabbit Anti-SYN3 Polyclonal Antibody,Synapsin-3, Synapsin III,SYN3 is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. The protein encoded by SYN3 shares the synapsin family domain model, with domains A, C, and E exhibiting the highest degree of conservation. The protein contains a unique domain J, located between domains C and E. Based on this gene's localization to 22q12. , a possible schizophrenia susceptibility locus, and the established neurobiological roles of the synapsins, this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of SYN3 and is transcribed in the opposite direction. Alternative splicing of SYN3 results in multiple splice variants that encode different isoforms.,SYN3
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Poids moléculaire
- observerd band 63kDa
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ID gène
- 8224
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UniProt
- O14994
Antigène
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