Synapsin III anticorps

N° du produit ABIN7231616

Cet anticorps anti-Synapsin III Polyclonal Lapin (ABIN7231616) détecte spécifiquement Synapsin III dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour Synapsin III anticorps (ABIN7231616)

Antigène: Synapsin III (SYN3)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Synapsin III est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Synapsin III anticorps

Fonction: Rabbit Anti-SYN3 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of SYN3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human SYN3 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Synapsin III

Antigène: Synapsin III (SYN3)

Autre désignation: SYN3

Sujet: Synapsin-3, Synapsin IIISYN3 is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. The protein encoded by SYN3 shares the synapsin family domain model, with domains A, C, and E exhibiting the highest degree of conservation. The protein contains a unique domain J, located between domains C and E. Based on this gene's localization to 22q12. , a possible schizophrenia susceptibility locus, and the established neurobiological roles of the synapsins, this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of SYN3 and is transcribed in the opposite direction. Alternative splicing of SYN3 results in multiple splice variants that encode different isoforms.

Poids moléculaire: 63kD

ID gène: 8224

UniProt: O14994