TCP1 alpha/CCTA anticorps (pSer455)
Aperçu rapide pour TCP1 alpha/CCTA anticorps (pSer455) (ABIN7213264)
Antigène
Voir toutes TCP1 alpha/CCTA (TCP1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer455
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Fonction
- p63 (phospho Ser455) Polyclonal Antibody
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Specificité
- Phospho-p63 (S455) Polyclonal Antibody detects endogenous levels of p63 protein only when phosphorylated at S455.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from human p63 Phospho-Ser455
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))
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Autre désignation
- p63
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Sujet
- Rabbit Anti-p63 (phospho Ser455) Polyclonal Antibody,TP63, KET, P63, P73H, P73L, TP73L, Tumor protein 63, p63, Chronic ulcerative stomatitis protein, CUSP, Keratinocyte transcription factor KET, Transformation-related protein 63, TP63, Tumor protein p73-like, p73L, p40, p51,TP63 encodes a member (tumor protein p63) of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of TP63 and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3), split-hand/foot malformation 4 (SHFM4), ankyloblepharon-ectodermal defects-cleft lip/palate, ADULT syndrome (acro-dermato-ungual-lacrimal-tooth), limb-mammary syndrome, Rap-Hodgkin syndrome (RHS), and orofacial cleft 8.,Tumor protein 63
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Poids moléculaire
- observerd band 70kDa
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ID gène
- 8626
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UniProt
- Q9H3D4
Antigène
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