TAO Kinase 1 (TAOK1) (AA 400-480) anticorps
Aperçu rapide pour TAO Kinase 1 (TAOK1) (AA 400-480) anticorps (ABIN7223798)
Antigène
Voir toutes TAO Kinase 1 (TAOK1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 400-480
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Fonction
- PSK2 Polyclonal Antibody
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Specificité
- PSK2 Polyclonal Antibody detects endogenous levels of PSK2 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from the Internal region of human PSK2 at AA range: 400-480
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- TAO Kinase 1 (TAOK1)
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Autre désignation
- PSK2
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Sujet
- Rabbit Anti-PSK2 Polyclonal Antibody,TAOK1, KIAA1361, MAP3K16, MARKK, Serine/threonine-protein kinase TAO1, Kinase from chicken homolog B, hKFC-B, MARK Kinase, MARKK, Prostate-derived sterile 20-like kinase 2, PSK-2, PSK2, Prostate-derived STE20-like kinase 2, Thousand and one,TAK1 is a mitogen-activated protein kinase kinase kinase that can be activated by TGF-β, bone morphogenetic protein and other cytokines including IL-1. In vivo activation of TAK1 requires association with TAK1 binding protein 1 (TAB1), which triggers phosphorylation of TAK1. Another adaptor protein, TAB2, links TAK1 with TRAF6 and mediates TAK1 activation upon IL-1 stimulation. Once activated, TAK1 phosphorylates MAPK kinases MKK4 and MKK3/6, which activate p38 MAPK and JNK, respectively. In addition, TAK1 activates the NF-κB pathway by interacting with TRAF6 and phosphorylating the NF-κB inducing kinase (NIK).,serine threonine-protein kinase TAO1
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Poids moléculaire
- observerd band 120kDa
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ID gène
- 57551
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UniProt
- Q7L7X3
Antigène
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