TSH receptor anticorps (AA 280-360)

N° du produit ABIN7231944

Cet anticorps anti-TSH receptor Polyclonal Lapin (ABIN7231944) détecte spécifiquement TSH receptor dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TSH receptor anticorps (AA 280-360) (ABIN7231944)

Antigène: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSH receptor est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TSH receptor anticorps

Épitope: AA 280-360

Fonction: Rabbit Anti-TSHR Polyclonal Antibody

Specificité: The antibody detects endogenous levels of TSHR protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human TSHR protein at AA range: 280-360

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur TSH receptor

Antigène: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Autre désignation: TSHR

Sujet: Thyrotropin receptor, Thyroid-stimulating hormone receptor, TSH-RReceptor for the thyroid-stimulating hormone (TSH) or thyrotropin (PubMed: 11847099, PubMed: 12045258). Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2: GPHB5) or thyrostimulin (PubMed: 12045258). The activity of this receptor is mediated by G proteins which activate adenylate cyclase (PubMed: 11847099). Plays a central role in controlling thyroid cell metabolism (By similarity).

Poids moléculaire: 84kD

ID gène: 7253

UniProt: P16473

Pathways: Thyroid Hormone Synthesis