TM2D1 anticorps

N° du produit ABIN7231836

Cet anticorps anti-TM2D1 Polyclonal Lapin (ABIN7231836) détecte spécifiquement TM2D1 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour TM2D1 anticorps (ABIN7231836)

Antigène: TM2D1 (TM2 Domain Containing 1 (TM2D1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TM2D1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TM2D1 anticorps

Fonction: Rabbit Anti-TM2D1 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of TM2D1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human TM2D1 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur TM2D1

Antigène: TM2D1 (TM2 Domain Containing 1 (TM2D1))

Autre désignation: TM2D1

Sujet: TM2 domain-containing protein 1, Amyloid-beta-binding protein, hBBPThe protein encoded by TM2D1 is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important in heterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative factor in neuron death and the consequent diminution of cognitive abilities observed in Alzheimer's disease. This protein may be a target of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to beta-amyloid peptide toxicity through a G protein-regulated program of cell death. Several transcript variants have been found for TM2D1.

Poids moléculaire: 22kD

ID gène: 83941

UniProt: Q9BX74