TGFBR1 anticorps

N° du produit ABIN7217298

Cet anticorps anti-TGFBR1 Polyclonal Lapin (ABIN7217298) détecte spécifiquement TGFBR1 dans WB, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TGFBR1 anticorps (ABIN7217298)

Antigène: TGFBR1 (Transforming Growth Factor, beta Receptor 1 (TGFBR1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TGFBR1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-TGFBR1 anticorps

Fonction: Rabbit Anti-TGFβ RI Polyclonal Antibody

Specificité: TGFβ RI Polyclonal Antibody detects endogenous levels of TGFβ RI protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human TGFbeta RI around the non-phosphorylation site of S165

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,IF 1:100-300,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur TGFBR1

Antigène: TGFBR1 (Transforming Growth Factor, beta Receptor 1 (TGFBR1))

Autre désignation: TGFbeta RI

Sujet: TGFBR1, ALK5, SKR4, TGF-beta receptor type-1, TGFR-1, Activin A receptor type II-like protein kinase of 53kD, Activin receptor-like kinase 5, ALK-5, ALK5, Serine/threonine-protein kinase receptor R4, SKR4, TGF-beta type I receptor, TransforTGF-beta receptor type-1 encoded by TGFBR1 forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The TGF-beta receptor type-1 is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 56kD

ID gène: 7046

UniProt: P36897

Pathways: Growth Factor Binding