Tropomyosin anticorps (N-Term)

N° du produit ABIN7217388

Cet anticorps Lapin Polyclonal détecte spécifiquement Tropomyosin dans WB et ELISA. Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour Tropomyosin anticorps (N-Term) (ABIN7217388)

Antigène: Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Tropomyosin est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Tropomyosin anticorps

Épitope: N-Term

Fonction: Tropomyosin α Polyclonal Antibody

Specificité: Tropomyosin α Polyclonal Antibody detects endogenous levels of Tropomyosin α protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the N-terminal region of human Tropomyosin alpha

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur Tropomyosin

Antigène: Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))

Autre désignation: Tropomyosin alpha

Sujet: Rabbit Anti-Tropomyosin α Polyclonal Antibody,TPM1, C15orf13, TMSA, Tropomyosin alpha-1 chain, Alpha-tropomyosin, Tropomyosin-1,TPM1 is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The tropomyosin alpha-1 chain is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.,Tropomyosin alpha-1 chain

Poids moléculaire: observerd band 35kDa

ID gène: 7168

UniProt: P09493

Pathways: Regulation of Actin Filament Polymerization