TUBGCP4 anticorps (AA 160-240)

N° du produit ABIN7215030

Cet anticorps Lapin Polyclonal détecte spécifiquement TUBGCP4 dans ELISA, WB, IHC et IF. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour TUBGCP4 anticorps (AA 160-240) (ABIN7215030)

Antigène: TUBGCP4 (Tubulin, gamma Complex Associated Protein 4 (TUBGCP4))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TUBGCP4 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-TUBGCP4 anticorps

Épitope: AA 160-240

Fonction: Rabbit Anti-GCP4 Polyclonal Antibody

Specificité: GCP4 Polyclonal Antibody detects endogenous levels of GCP4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human GCP4 at AA range: 160-240

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur TUBGCP4

Antigène: TUBGCP4 (Tubulin, gamma Complex Associated Protein 4 (TUBGCP4))

Autre désignation: GCP4

Sujet: TUBGCP4, 76P, GCP4, Gamma-tubulin complex component 4, GCP-4, hGCP4, Gamma-ring complex protein 76 kDa, h76p, hGrip76TUBGCP4 encodes a component of the gamma-tubulin ring complex, gamma-tubulin complex component 4, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 76kD

ID gène: 27229

UniProt: Q9UGJ1

Pathways: M Phase