Tumor Protein p73 anticorps (pTyr99)

N° du produit ABIN7213102

Cet anticorps anti-Tumor Protein p73 Polyclonal Lapin (ABIN7213102) détecte spécifiquement Tumor Protein p73 dans WB, IHC, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour Tumor Protein p73 anticorps (pTyr99) (ABIN7213102)

Antigène: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Tumor Protein p73 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-Tumor Protein p73 anticorps

Épitope: pTyr99

Fonction: Rabbit Anti-p73 (phospho Tyr99) Polyclonal Antibody

Specificité: Phospho-p73 (Y99) Polyclonal Antibody detects endogenous levels of p73 protein only when phosphorylated at Y99.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human p73 Phospho-Tyr99

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Tumor Protein p73

Antigène: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Autre désignation: p73

Sujet: TP73, P73, Tumor protein p73, p53-like transcription factor, p53-related proteinTP73 encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that TP73 is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for TP73, but the biological validity and the full-length nature of some variants have not been determined.

Poids moléculaire: 73kD

ID gène: 7161

UniProt: O15350

Pathways: Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus