TUSC5 anticorps (AA 10-90)

N° du produit ABIN7221268

Cet anticorps Lapin Polyclonal détecte spécifiquement TUSC5 dans ELISA, WB et IHC. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour TUSC5 anticorps (AA 10-90) (ABIN7221268)

Antigène: TUSC5 (Tumor Suppressor Candidate 5 (TUSC5))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TUSC5 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-TUSC5 anticorps

Épitope: AA 10-90

Fonction: Rabbit Anti-LOST1 Polyclonal Antibody

Specificité: LOST1 Polyclonal Antibody detects endogenous levels of LOST1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the N-terminal region of human LOST1 at AA range: 10-90

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur TUSC5

Antigène: TUSC5 (Tumor Suppressor Candidate 5 (TUSC5))

Autre désignation: LOST1

Sujet: TUSC5, IFITMD3, LOST1, Tumor suppressor candidate 5, Dispanin subfamily B member 1, DSPB1, Interferon-induced transmembrane domain-containing protein D3, Protein located at seventeen-p-thirteen point three 1TUSC5 (tumor suppressor candidate 5), also known as protein located at seventeen-p-thirteen point three 1, LOST1 or IFITMD3 (interferon-induced transmembrane domain-containing protein D3), is a 177 amino acid multi-pass membrane protein that belongs to the CD225 family. Thought to play a role in fat metabolism, TUSC5 is highly expressed in mammary gland, heart, smooth muscle, skeletal muscle and stomach, with lower levels found in lung and brain. The gene encoding TUSC5 maps to human chromosome 17, which comprises over 2. % of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, and is liked to predisposition of cancers of the ovary, colon, prostate gland and fallopian tubes.

Poids moléculaire: 22kD

ID gène: 286753

UniProt: Q8IXB3