USP11 anticorps (Internal Region)

N° du produit ABIN7218842

L’anticorps Lapin Polyclonal anti-USP11 a été validé pour WB et ELISA. Il convient pour détecter USP11 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour USP11 anticorps (Internal Region) (ABIN7218842)

Antigène: USP11 (Ubiquitin Specific Peptidase 11 (USP11))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP11 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-USP11 anticorps

Épitope: Internal Region

Fonction: USP11 Polyclonal Antibody

Specificité: USP11 Polyclonal Antibody detects endogenous levels of USP11 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the Internal region of human USP11

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur USP11

Antigène: USP11 (Ubiquitin Specific Peptidase 11 (USP11))

Autre désignation: USP11

Sujet: Rabbit Anti-USP11 Polyclonal Antibody,USP11, UHX1, Ubiquitin carboxyl-terminal hydrolase 11, Deubiquitinating enzyme 11, Ubiquitin thioesterase 11, Ubiquitin-specific-processing protease 11,USP11 (Ubiquitin Specific Peptidase 11) is a Protein Coding gene. Among its related pathways are Transport to the Golgi and subsequent modification and Chaperonin-mediated protein folding. GO annotations related to this gene include cysteine-type endopeptidase activity and thiol-dependent ubiquitinyl hydrolase activity. An important paralog of this gene is USP4. rotease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains (PubMed: 12084015, PubMed: 15314155, PubMed: 17897950, PubMed: 19874889, PubMed: 20233726, PubMed: 24724799). Inhibits the degradation of target proteins by the proteasome (PubMed: 12084015). Cleaves preferentially Lys-6 and Lys-63-linked ubiquitin chains. Has lower activity with Lys-11 and Lys-33-linked ubiquitin chains, and extremely low activity with Lys-27, Lys-29 and Lys-48-linked ubiquitin chains (in vitro) (PubMed: 24724799). Plays a role in the regulation of pathways leading to NF-kappa-B activation (PubMed: 17897950, PubMed: 19874889). Plays a role in the regulation of DNA repair after double-stranded DNA breaks (PubMed: 15314155, PubMed: 20233726).,Ubiquitin carboxyl-terminal hydrolase 11

Poids moléculaire: observerd band 105kDa

UniProt: P51784