UBE2D3 anticorps

N° du produit ABIN7231980

L’anticorps anti-UBE2D3 Polyclonal Lapin est utilisé pour la détection de UBE2D3 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour UBE2D3 anticorps (ABIN7231980)

Antigène: UBE2D3 (Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE2D3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-UBE2D3 anticorps

Fonction: Rabbit Anti-UB2D3 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of UB2D3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human UB2D3 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur UBE2D3

Antigène: UBE2D3 (Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3))

Autre désignation: UB2D3

Sujet: Ubiquitin-conjugating enzyme E2 D3, E2 ubiquitin-conjugating enzyme D3, Ubiquitin carrier protein D3, Ubiquitin-conjugating enzyme E2-17 kDa 3, Ubiquitin-protein ligase D3UBE2D3 (Ubiquitin Conjugating Enzyme E2 D3) is a Protein Coding gene. Diseases associated with UBE2D3 include Retinitis Pigmentosa 42. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and Protein processing in endoplasmic reticulum. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D3 encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.

Poids moléculaire: 16kD

ID gène: 7323

UniProt: P61077

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades