UBE2K anticorps
Aperçu rapide pour UBE2K anticorps (ABIN7231998)
Antigène
Voir toutes UBE2K AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Rabbit Anti-UBE2K Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of UBE2K protein
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from part region of human UBE2K protein
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))
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Autre désignation
- UBE2K
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Sujet
- Ubiquitin-conjugating enzyme E2 K, E2 ubiquitin-conjugating enzyme K, Huntingtin-interacting protein 2, HIP-2, Ubiquitin carrier protein, Ubiquitin-conjugating enzyme E2-25 kDa, Ubiquitin-conjugating enzyme E2-25K, Ubiquitin-protein ligaseUBE2K (Ubiquitin Conjugating Enzyme E2 K) is a Protein Coding gene. Among its related pathways are Protein ubiquitination and Class I MHC mediated antigen processing and presentation. The protein encoded by UBE2K belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for UBE2K.
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Poids moléculaire
- 22kD
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ID gène
- 3093
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UniProt
- P61086
Antigène
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