UBE4A anticorps (Internal Region)
Aperçu rapide pour UBE4A anticorps (Internal Region) (ABIN7218944)
Antigène
Voir toutes UBE4A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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Fonction
- Rabbit Anti-UFD2 Polyclonal Antibody
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Specificité
- UFD2 Polyclonal Antibody detects endogenous levels of UFD2 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from the Internal region of human UFD2
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- UBE4A (Ubiquitination Factor E4A (UBE4A))
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Autre désignation
- UFD2
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Sujet
- UBE4B, HDNB1, KIAA0684, UFD2, Ubiquitin conjugation factor E4 B, Homozygously deleted in neuroblastoma 1, Ubiquitin fusion degradation protein 2The ubiquitination factor E4B with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE4B encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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ID gène
- 10277
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UniProt
- O95155
Antigène
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