UBXN11 anticorps (AA 100-180)

N° du produit ABIN7225846

L’anticorps anti-UBXN11 Polyclonal Lapin est utilisé pour la détection de UBXN11 dans des échantillons de Humain, Souris et Rat. Il a été validé pour ELISA, IHC, WB et IF.

Aperçu rapide pour UBXN11 anticorps (AA 100-180) (ABIN7225846)

Antigène: UBXN11 (UBX Domain Protein 11 (UBXN11))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBXN11 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-UBXN11 anticorps

Épitope: AA 100-180

Fonction: Rabbit Anti-Socius Polyclonal Antibody

Specificité: Socius Polyclonal Antibody detects endogenous levels of Socius protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human Socius at AA range: 100-180

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur UBXN11

Antigène: UBXN11 (UBX Domain Protein 11 (UBXN11))

Autre désignation: Socius

Sujet: UBXN11, SOC, UBXD5, PP2243, UBX domain-containing protein 11, Colorectal tumor-associated antigen COA-1, Socius, UBX domain-containing protein 5UBXN11 (UBX domain protein 11) encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways. The 3' coding sequence of UBXN11 contains a polymoprhic region of 24 nt tandem repeats. Several transcripts containing between 1. and five repeat units have been reported. Multiple transcript variants encoding different isoforms have been found for UBXN11.

Poids moléculaire: 57kD

ID gène: 91544

UniProt: Q5T124