UGDH anticorps (AA 360-440)

N° du produit ABIN7224864

Cet anticorps anti-UGDH Polyclonal Lapin (ABIN7224864) détecte spécifiquement UGDH dans WB, ELISA et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour UGDH anticorps (AA 360-440) (ABIN7224864)

Antigène: UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UGDH est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-UGDH anticorps

Épitope: AA 360-440

Fonction: UDP-GlcDH Polyclonal Antibody

Specificité: UDP-GlcDH Polyclonal Antibody detects endogenous levels of UDP-GlcDH protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the C-terminal region of human UDP-GlcDH at AA range: 360-440

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur UGDH

Antigène: UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))

Autre désignation: UDP-GlcDH

Sujet: Rabbit Anti-UDP-GlcDH Polyclonal Antibody,UGDH, UDP-glucose 6-dehydrogenase, UDP-Glc dehydrogenase, UDP-GlcDH, UDPGDH,The protein encoded by UGDH (UDP-glucose 6-dehydrogenase) converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of UGDH is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.,UDP-glucose 6-dehydrogenase

Poids moléculaire: observerd band 55kDa

ID gène: 7358

UniProt: O60701

Pathways: Glycosaminoglycan Metabolic Process