ULBP2 anticorps
Aperçu rapide pour ULBP2 anticorps (ABIN7229878)
Antigène
Voir toutes ULBP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- N2DL2 Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of N2DL2 protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogène
- Synthesized peptide derived from part region of human N2DL2 protein
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- ULBP2 (UL16 Binding Protein 2 (ULBP2))
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Autre désignation
- N2DL2
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Sujet
- Rabbit Anti-N2DL2 Polyclonal Antibody,UL16-binding protein 2, ALCAN-alpha, NKG2D ligand 2, N2DL-2, NKG2DL2, Retinoic acid early transcript 1H,ULBP2 encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. ULBP2 is located in a cluster of multiple MHC class I-related genes on chromosome 6. ULBP2 (UL16 Binding Protein 2) is a Protein Coding gene. Among its related pathways are Immune response Role of DAP12 receptors in NK cells and p53 Pathway (RnD).,N2DL2
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Poids moléculaire
- observerd band 27kDa
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ID gène
- 80328
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UniProt
- Q9BZM5
Antigène
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