UNC5D anticorps (AA 160-240)
Aperçu rapide pour UNC5D anticorps (AA 160-240) (ABIN7232044)
Antigène
Voir toutes UNC5D AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 160-240
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Fonction
- Rabbit Anti-UNC5D Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of UNC5D protein
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from part region of human UNC5D protein at AA range: 160-240
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- UNC5D (Unc-5 Homolog D (UNC5D))
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Autre désignation
- UNC5D
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Sujet
- Netrin receptor UNC5D, Protein unc-5 homolog 4, Protein unc-5 homolog DReceptor for the netrin NTN4 that promotes neuronal cell survival. Plays a role in cell-cell adhesion and cell guidance. Receptor for netrin involved in cell migration. Plays a role in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. May play a role in apoptosis in response to DNA damage. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (PubMed: 24519068). Mediates cell-cell adhesion via its interaction with FLRT3 on an adjacent cell.
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Poids moléculaire
- 104kD
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ID gène
- 137970
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UniProt
- Q6UXZ4
Antigène
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