Uromodulin anticorps (Internal Region)

N° du produit ABIN7224866

Cet anticorps anti-Uromodulin est un anticorps Lapin Polyclonal détectant Uromodulin dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour Uromodulin anticorps (Internal Region) (ABIN7224866)

Antigène: Uromodulin (UMOD)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Uromodulin est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Uromodulin anticorps

Épitope: Internal Region

Fonction: THP Polyclonal Antibody

Specificité: THP Polyclonal Antibody detects endogenous levels of THP protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the Internal region of human THP

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur Uromodulin

Antigène: Uromodulin (UMOD)

Autre désignation: THP

Sujet: Rabbit Anti-THP Polyclonal Antibody,UMOD, Uromodulin, Tamm-Horsfall urinary glycoprotein, THP,The protein encoded by UMOD (uromodulin) is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in UMOD are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of UMOD results in multiple transcript variants.,Uromodulin

Poids moléculaire: observerd band 70kDa

ID gène: 7369

UniProt: P07911