Vimentin anticorps (pTyr61)

N° du produit ABIN7224922

Cet anticorps Lapin Polyclonal détecte spécifiquement Vimentin dans WB et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour Vimentin anticorps (pTyr61) (ABIN7224922)

Antigène: Vimentin (VIM)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Vimentin est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Vimentin anticorps

Épitope: pTyr61

Fonction: Vimentin (phospho Tyr61) Polyclonal Antibody

Specificité: Phospho-Vimentin (Y61) Polyclonal Antibody detects endogenous levels of Vimentin protein only when phosphorylated at Y61.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from human Vimentin Phospho-Tyr61

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur Vimentin

Antigène: Vimentin (VIM)

Autre désignation: Vimentin

Sujet: Rabbit Anti-Vimentin (phospho Tyr61) Polyclonal Antibody,VIM, Vimentin,VIM (vimentin) encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by VIM is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in VIM causes a dominant, pulverulent cataract.,Vimentin

Poids moléculaire: observerd band 57kDa

ID gène: 7431

UniProt: P08670

Pathways: Caspase Cascade in Apoptosis