TSHZ3 anticorps

N° du produit ABIN7231940

Cet anticorps anti-TSHZ3 Polyclonal Lapin (ABIN7231940) détecte spécifiquement TSHZ3 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TSHZ3 anticorps (ABIN7231940)

Antigène: TSHZ3 (Teashirt Zinc Finger Homeobox 3 (TSHZ3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSHZ3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TSHZ3 anticorps

Fonction: Rabbit Anti-TSH3 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of TSH3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human TSH3 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur TSHZ3

Antigène: TSHZ3 (Teashirt Zinc Finger Homeobox 3 (TSHZ3))

Autre désignation: TSH3

Sujet: Teashirt homolog 3, Zinc finger protein 537TSHZ3 (Teashirt Zinc Finger Homeobox 3) encodes a zinc-finger transcription factor that regulates smooth muscle cell differentiation in the developing urinary tract. Consistent with this role, mice in which TSHZ3 has been inactivated exhibit abnormal gene expression in urinary tract smooth muscle cell precursors and kidney defects including hydronephrosis. The encoded transcription factor comprises a gene silencing complex that inhibits caspase expression. Reduced expression of TSHZ3 and consequent caspase upregulation may be correlated with progression of Alzheimer's disease in human patients. TSHZ3 is a Protein Coding gene. Diseases associated with TSHZ3 include Hydronephrosis and Endemic Goiter.

Poids moléculaire: 118kD

ID gène: 57616

UniProt: Q63HK5

Pathways: Regulation of Muscle Cell Differentiation