Cet anticorps anti-ZCCHC17 Polyclonal Lapin (ABIN7223034) détecte spécifiquement ZCCHC17 dans ELISA, IHC et IF.
L’anticorps est réactif avec des échantillons de Humain et Souris.
ZCCHC17
Reactivité: Humain
ELISA
Hôte: Lapin
Polyclonal
HRP
Indications d'application
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
ZCCHC17, PS1D, HSPC243, HSPC251, LDC4, Nucleolar protein of 40 kDa, pNO40, Pnn-interacting nucleolar protein, Putative S1 RNA-binding domain protein, PS1D protein, Zinc finger CCHC domain-containing protein 17Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZCCHC17 (zinc finger, CCHC domain containing 17), also known as PS1D (putative S1 RNA-binding domain protein), Pnn (Pinin)-interacting nucleolar protein or pNO40, is a 241 amino acid protein that associates with both Pinin and the 60S ribosomal subunit. Localizing to nucleolus, ZCCHC17 is ubiquitously expressed and has been suggested to play a role in ribosome maturation and biogenesis. ZCCHC17 contains one CCHC-type zinc finger, a S1 motif domain and exists as two alternatively spliced isoforms that map to human chromosome 1p35.2. Human chromosome 1 spans 260 million base pairs, contains over 3000 genes, comprises nearly 8 % of the human genome and houses a large number of disease-associated genes, including those that are involved in Stickler syndrome, Parkinson's disease, Gaucher disease and Usher syndrome.