TRPV3 anticorps (C-Term)

N° du produit ABIN7232803

Cet anticorps Souris Monoclonal détecte spécifiquement TRPV3 dans WB, IHC, IP et IF/ICC. Il présente une réactivité avec des échantillons de Rat.

Aperçu rapide pour TRPV3 anticorps (C-Term) (ABIN7232803)

Antigène: TRPV3 (Transient Receptor Potential Cation Channel, Subfamily V, Member 3 (TRPV3))

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TRPV3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (fixed cells) (IF/ICC)

Clone: S15-4

Détail du produit anti-TRPV3 anticorps

Épitope: AA 458-474, C-Term

Fonction: Anti-TrpV3 Cation Channel Mouse Monoclonal Antibody

Specificité: This antibody recognizes human, mouse, and rat TrpV3.

Réactivité croisée: Humain, Souris, Rat

Immunogène: Synthetic peptide corresponding to aa 458-474 (cytoplasmic C-terminus) of rat TrpV3 (accession no. NP_001020928).

Isotype: IgG2a

Information d'application

Indications d'application: Immunoblotting: use at 1-10 μg/mL. A band of ~70 kDa is detected.Immunohistochemistry and
Immunocytochemistry: use at 0.1-1 μg/mL
Immunofluorescence: use at 1-10 μg/mL
These are recommended concentrations. User should determine optimal concentrations for their application.
Positive control: COS cell lysate transiently transfected with TrpM7.

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: Dilute in PBS or medium which is identical to that used in the assay system.

Concentration: Lot specific

Buffer: PBS, pH 7.4, 50 % glycerol, 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: This antibody is stable for at least one (1) year at -20°C.

Détails sur TRPV3

Antigène: TRPV3 (Transient Receptor Potential Cation Channel, Subfamily V, Member 3 (TRPV3))

Autre désignation: TrpV3 Cation Channel

Sujet: Heat sensitive channel TRPV3,Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. The TrpV3 protein belongs to a family of nonselective cation channels that function in a variety of processes including temperature sensation and vasoregulation. The thermosensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin and are activated at distinct physiological temperatures. The TrpV3 channel is activated at temperatures between 22 and 40 C. The TrpV3 gene is in close proximity to the TrpV1 gene on chromosome 17, and studies suggest that the corresponding two proteins associate with each other to form heteromeric channels.

NCBI Accession: NP_001020928

UniProt: Q4QYD9