Glutathione Reductase anticorps (AA 44-522)

N° du produit ABIN7232834

L’anticorps anti-Glutathione Reductase Monoclonal Souris est utilisé pour la détection de Glutathione Reductase dans des échantillons de Humain. Il a été validé pour WB et ELISA.

Aperçu rapide pour Glutathione Reductase anticorps (AA 44-522) (ABIN7232834)

Antigène: Glutathione Reductase (GSR)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Glutathione Reductase est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 2A2-1B7

Détail du produit anti-Glutathione Reductase anticorps

Épitope: AA 44-522

Fonction: Anti-Glutathione Reductase Mouse Monoclonal Antibody

Specificité: These antibodies recognize human glutathione reductase. They do not cross-react with yeast glutathione reductase.

Réactivité croisée: Humain

Immunogène: Recombinant human glutathione reductase purified from E. coli expressing the human glutathione reductase gene (aa 44-522).

Isotype: IgG1

Information d'application

Indications d'application: ELISA: Titration of glutathione reductase MAbs with glutathione reductase at 3 μg/mL on the wells.ELISA Pairs: Both of these antibodies function as capture and detection antibodies at 1 μg/mL.
Immunoblotting: use at 0.5-1.0 μg/mL. A band of ~57 kDa is detected.
These are recommended concentrations.
Endusers should determine optimal concentrations for their applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: Dilute in PBS or medium that is identical to that used in the assay system.

Concentration: Lot specific

Buffer: PBS, pH 7.4

Stock: -20 °C

Stockage commentaire: These antibodies are stable for at least one (1) year at -20°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.

Détails sur Glutathione Reductase

Antigène: Glutathione Reductase (GSR)

Autre désignation: GSR

Sujet: Glutathione reductase, mitochondrial,Maintains high levels of reduced glutathione in the cytosol.,Glutathione reductase, also known as glutathione-disulfide reductase, is an enzyme that in humans is encoded by the GSR gene. Glutathione reductase catalyzes the reduction of glutathione disulfide to the sulfhydryl form glutathione (GSH), which is a critical molecule in resisting oxidative stress and maintaining the reducing environment of the cell. The importance of the glutathione pathway and enzymes that affect it is gaining an increased level of attention. Although glutathione reductase has been an attractive target for many pharmaceuticals, there have been no successful glutathione reductase related therapeutic compounds created to date.,[Isoform Mitochondrial]: Mitochondrion., [Isoform Cytoplasmic]: Cytoplasm.,GR, GRase, EC 1.8.1.7

NCBI Accession: NP_000628

UniProt: P00390

Pathways: Thyroid Hormone Synthesis, Cell RedoxHomeostasis