CHGB anticorps (C-Term)

N° du produit ABIN7232896

Cet anticorps Lapin Polyclonal détecte spécifiquement CHGB dans WB. Il présente une réactivité envers Rat.

Aperçu rapide pour CHGB anticorps (C-Term) (ABIN7232896)

Antigène: CHGB (Chromogranin B (Secretogranin 1) (CHGB))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHGB est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CHGB anticorps

Épitope: AA 641-655, C-Term

Fonction: Anti-Chromogranin B Rabbit Polyclonal Antibody

Specificité: This antibody recognizes human, mouse, and rat chromogranin B.

Réactivité croisée: Humain, Souris, Rat

Immunogène: Synthetic peptide derived from the C-terminus (aa 641-655) of CgB (accession no. NP_001810. This sequence is identical in human, mouse, and rat CgB.

Information d'application

Indications d'application: Immunoblotting: use at 0.1-1.0 μg/mL
These are recommended concentrations.
Enduser should determine optimal concentrations for their applications.Although the predicted mw of CgB is ~76 kDa, the highly acidic nature of CgB causes it to run at a higher mw in SDS-PAGE.
Immunohistochemistry: use at 1-5 μg/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: Dilute in PBS or medium that is identical to that used in the assay system.

Concentration: Lot specific

Buffer: PBS, pH 7.4

Stock: -20 °C,-80 °C

Stockage commentaire: This antibody is stable for at least one (1) year at -20°C to -70°C. Avoid multiple freeze-thaw cycles.

Détails sur CHGB

Antigène: CHGB (Chromogranin B (Secretogranin 1) (CHGB))

Autre désignation: CHGB

Sujet: Secretogranin-1,Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides.,Chromogranin B (CgB, secretogranin I) is a secretory granule matrix protein expressed in a wide variety of endocrine cells and neurons where it may have both extracellular and intracellular functions. Extracellular roles for CgB are dependent on its proteolytic processing within secretory granules to form smaller peptides that may have a role in the neuroendocrine/sympathoadrenal stress response to systemic infection, and CgB fragments may also have an autocrine inhibitory role in the release of co-stored hormones, such as insulin.,Secreted. Note=Neuroendocrine and endocrine secretory granules.,Chromogranin-B, CgB, Secretogranin I, SgI [Cleaved into: PE-11, GAWK peptide, CCB peptide]

UniProt: P05060