GIT1 anticorps (C-Term)
Aperçu rapide pour GIT1 anticorps (C-Term) (ABIN7233038)
Antigène
Voir toutes GIT1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 375-770, C-Term
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Fonction
- Anti-GIT1 Mouse Monoclonal Antibody
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Specificité
- This antibody recognizes human, mouse and rat GIT1. It does not cross-react with GIT2.
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Réactivité croisée
- Humain, Souris, Rat
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Purification
- Purified by Protein G affinity chromatography.
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Immunogène
- Fusion protein corresponding to aa 375-770 (C-terminus) of rat GIT1 (accession no.Q9Z272).
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Isotype
- IgG1
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Indications d'application
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Immunoblotting: use at 1 μg/mL. Predicted molecular weight is ~90 kDa.
Positive control: rat brain lysate.
These are recommended concentrations.
Endusers should determine optimal concentrations for their applications. -
Restrictions
- For Research Use only
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Format
- Liquid
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Reconstitution
- Dilute in PBS or medium that is identical to that used in the assay system.
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.4, 50 % glycerol, 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- This antibody is stable for at least one (1) year at -20°C.
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- GIT1
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Autre désignation
- Git1
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Sujet
- ARF GTPase-activating protein GIT1,G-protein coupled receptor (GPCR) kinase interacting proteins 1 and 2 (GIT1 and GIT2) are highly conserved ubiquitous scaffold proteins involved in localized signaling to help regulate focal contact assembly and cytoskeletal dynamics. GIT proteins contain multiple interaction domains for small GTPases, kinases, the Rho family GEF PIX, and the focal adhesion protein paxillin. GIT1 is localized to focal adhesions, cyto- plasmic complexes and membrane protrusions, and it regulates cell protrusion formation and cell migration.
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UniProt
- Q9Z272
Antigène
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