Neuroligin 3 anticorps (C-Term)
Aperçu rapide pour Neuroligin 3 anticorps (C-Term) (ABIN7233050)
Antigène
Voir toutes Neuroligin 3 (NLGN3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 730-848, C-Term
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Fonction
- Anti-Neuroligin-3 Mouse Monoclonal Antibody
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Specificité
- This antibody recognizes human, mouse and rat Neuroligin-3. It does not cross- react with Neuroligin-1, -2, or -4.
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Réactivité croisée
- Humain, Souris, Rat
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Immunogène
- Fusion protein corresponding to aa 730-848 (intracellular C-terminus) of rat Neuroligin- 3. This sequence is 99
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Isotype
- IgG1
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Indications d'application
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Immunoblotting: use at 1-5 μg/mL. A band of ~110 kDa is detected.
Immunofluorescence: use at 10 μg/mL.
These are recommended concentrations.
Endusers should determine optimal concentrations for their application. -
Restrictions
- For Research Use only
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Format
- Liquid
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Reconstitution
- Dilute in PBS or medium that is identical to that used in the assay system.
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.4, 0.1 % sodium azide, 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- This product is stable for at least one (1) year at -20°C.
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- Neuroligin 3 (NLGN3)
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Autre désignation
- Nlgn3
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Sujet
- Neuroligin-3,Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system. {PubMed:17897391}.,Neuroligin-3 is a neuronal cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. It plays a role in synapse function and synaptic signal transmission, and may mediate its effects by clustering other synaptic proteins. It may also promote the initial formation of synapses and play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene.,Cell membrane, Single-pass type I membrane protein. Cell junction, synapse. Note=Detected at both glutamatergic and GABAergic synapses.,Gliotactin homolog
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UniProt
- Q62889
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Pathways
- Synaptic Membrane
Antigène
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